Write to Machine's PLC

Hello guys,
Is there any way to write data from Tulip to Machines’ PLCs.
NB : Actually i am using Kepserver (OPC UA) to get data from the machines API so can i do the same thing but in the other way (from tulip to machine’s PLC using kepserver or an other way).

Yes with Kepware gateway that can expose OPC UA write method in REST protocol.